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Reproducibility is one of the main principles of the scientific method, and refers to the ability of a test or experiment to be accurately reproduced, or replicated, by someone else working independently.

Reproducibility is different from repeatability, which measures the success rate in successive experiments, possibly conducted by the same experimenters. Reproducibility relates to the agreement of test results with different operators, test apparatus, and laboratory locations. It is often reported as a standard deviation.

While repeatability of scientific experiments is desirable, it is not considered necessary to establish the scientific validity of a theory. For example, the cloning of animals is difficult to repeat, but has been reproduced by various teams working independently, and is a well established research domain. One failed cloning does not mean that the theory is wrong or unscientific. Repeatability is often low in protosciences.

The results of an experiment performed by a particular researcher or group of researchers are generally evaluated by other independent researchers by reproducing the original experiment. They repeat the same experiment themselves, based on the original experimental description, and see if their experiment gives similar results to those reported by the original group. The result values are said to be commensurate if they are obtained (in distinct experimental trials) according to the same reproducible experimental description and procedure.

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