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Binary fission is the form of asexual reproduction and cell division used by prokaryotic organisms (such as bacteria or archaea). This process results in the reproduction of a living prokaryotic cell by division into two parts which each have the potential to grow to the size of the original cell Organisms that reproduce through binary fission generally have exponential growth phases. Escherichia coli cells are able to divide every 20 minutes under optimum conditions. Binary fission begins with DNA replication. DNA replication starts from an origin of replication, which opens up into a replication bubble (note prokaryotic DNA replication usually has only 1 origin of replication, whereas eukaryotes have multiple origins of replication). The replication bubble separates the DNA double strand, each strand acts as template for synthesis of a daughter strand by semiconservative replication, until the entire prokaryotic DNA is duplicated. After this replicational process, cell growth occurs.
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